Sertraline Medication

Interaction Between Sertraline Medication And Other Medicines

An interaction between two medications does not always mean that you must stop taking one of them. In many cases, interactions are intended or are managed by close monitoring. Speak to your doctor about how any drug interactions are being managed or should be managed.

Like other medicines that belong to SSRIs, Sertraline should not be used in combination with MAOIs. The following agents may affect the way that sertraline works or increase the risk of side effects:

• alcohol
• certain antiarrhythmic medications (e.g., flecainide, propafenone)
• cimetidine
• lithium
• MAO inhibitors (e.g., phenelzine, tranylcypromine, moclobemide)
• other SSRIs (e.g., paroxetine, fluoxetine, citalopram, fluvoxamine)
• sibutramine
• tricyclic antidepressants (e.g., amitriptyline, imipramine, nortriptyline)
• tryptophan

The following medications may be affected by sertraline or increase the risk of side effects:

• pimozide
• warfarin

The following dietary supplements may be affected by sertraline or increase the risk of side effects:

• 5-Hydroxytryptophan (5-HTP)
• L-tryptophan
• St. John’s wort

Medicines other than those listed above may interact with Sertraline medication.